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CONTRACTED MANUFACTUREPHARMACEUTICAL

Advanced scale-up technology

イメージ Scale-up from laboratory to production The scale-up technology gained by manufacturing more than 500 types per year enables us to scale-up from laboratory to production. Therefore, we can supply the products in a shorter time. イメージ Control of crystal shapes in crystallization The optimum conditions can be efficiently searched for in a database containing abundant information on the crystallization of organic chemical compounds. イメージ Thermodynamic simulation We measure the heating value by a reaction calorimeter. The simulation is performed based on the data of the actual reactor. イメージ Small-scale examination for milling condition Our test mill can simulate operations at a 10g scale or smaller. The appropriate mill type and conditions for achieving target particle size can be found. イメージ Scale-up simulation of crystal filtration Filtration with production equipment is simulated by using centrifugal filtration test equipment. Problems with filtration properties can be improved using our crystallization technology. イメージ Scale-up simulation of crystal drying Short time consistent quality drying conditions are determined by the use of conical drying test equipment. For instance, stable upscaling is achieved through continuous rotation to prevent conglomerate crystallization and by using mechanical impacts to check for crystal dislocation.
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