Polymer-related chemicals


Water soluble monomer

Water solubleBiocompatibleStable

Plastics manufacturing


FOM-03010 is a Fujifilm's unique novel monomer containing a betaine structure and a methacrylamide group that exhibits high hydrophilicity. It is highly hydrophilic and biocompatible as well as stable.

Chemical name [3-(Methacryloylamino)propyl]dimethyl(3-sulfobutyl)ammonium hydroxide inner salt
CAS RN® 83623-32-9

Physical characteristics

Physical characteristics Form Powder
Color White
Odor Odorless
Melting point None

Related laws and regulations

TSCA Not Listed
EINECS Not Listed
REACH Not Listed


1) Highly water soluble and hydrophilic

  • FOM-03010 dissolves in water at 50 wt% or more. It is easily soluble in solvents such as methanol and ethanol.
  • Due to the betaine structure, it exhibits very high hydrophilicity. (CLogP = -10)

Many of the hydrophilic monomers currently on the market have CLogP values of around -2 to +1, which is an index of hydrophilicity/hydrophobicity.
FOM-03010 has a CLogP value of -10 and much higher hydrophilicity than these general-purpose monomers.


Also in the LogD value, which is a hydrophilicity index considering the dissociation of molecules under different pH environments, FOM-03010 shows high hydrophilicity with LogD = -4 (pH = 7).

MPC:2-Methacryloyloxyethyl phosphorylcholine
GLBT:Carboxymethyl betaine monomer
HEMA:2-Hydroxyethyl methacrylate

Solubility in various solvents and monomers

Solvent/monomer name Solubility at each solid content concentration (weight%)
0.1 0.5 1 10 20 30 40 50
Methanol × -
Ethanol × - - -
Isopropyl alcohol × - - - - -
Dimethylsulfoxide × - -
Acetone × - - - - - - -
Ethyl acetate × - - - - - - -
Dimethylacetamide × - - - - - - -
2-Hydroxyethyl methacrylate
× - - -
N-(2-Hydroxyethyl) acrylamide × - -
N,N-Dimethylacrylamide × - - - - - -
4-Acryloyl morpholine × - - - - - -

※Measured at liquid temperature of 25°C
※ 🞅: Soluble 🞨: Insoluble -: Not measured

2) Excellent in hydrolysis resistance

  • Excellent in hydrolytic resistance in acidic to basic aqueous solutions.

3) Highly biocompatible

  • Resistant to cell adhesion and platelet adhesion. *Based on the test by FUJIFILM

Verification of the inhibitory effect of cell adhesion



Imparting biocompatibility to various products

Examples:Medical devices, materials for analytical instruments, materials for bioengineering

Hydrophilic/antifouling coating

Examples:Separating film, analytical instruments, building materials, water-absorbing materials, fibers, household products, cleaning agents

Water retaining/moisturizing materials

Examples:Additives for cosmetics and toiletry products, civil engineering materials, sanitary goods

Control of hydrophilicity/hydrophobicity of various cured components

Examples:Paint, coating, kneaded and molded products, printing materials, gel, drug formulation materials

Usage example

  • A functional coat with a high hydrophilicity can be formed.
  • Due to the high water solubility of the monomer and initiator, a coat solution can be prepared using water as a solvent.

Example of composition of Coat A

Name of raw material Compounding ratio (wt%)
Water soluble crosslinking agent (FOM-03006) 30
Water soluble monomer (FOM-03010) 67
Water soluble light radical initiator (FOM-03011) 3
Methanol 400

Usage example and physical characteristics of Coat A

  • Apply to PET substrate, dry (50°C/5 min), and then photocure (3 J/cm2)

※Lamp used: High pressure mercury lamp (Exposure is controlled as UV-A)

Coats evaluated Water contact angle (°)
PET alone 75
Coat A 35
Impregnate Coat A with water and dry 44

In evaluation of wettability by water contact angle showing affinity with water, Coat A exhibits high hydrophilicity with a low contact angle, and maintains the hydrophilicity even when it is re-dried after being impregnated with water.