FOM-03010
Water soluble monomer
 
				 
				 
			Plastics manufacturing
Photocurable
FOM-03010 is a Fujifilm's unique novel monomer containing a betaine structure and a methacrylamide group that exhibits high hydrophilicity. It is highly hydrophilic and biocompatible as well as stable.
 
			| Chemical name | [3-(Methacryloylamino)propyl]dimethyl(3-sulfobutyl)ammonium hydroxide inner salt | 
|---|---|
| CAS RN® | 83623-32-9 | 
Physical characteristics
| FOM-03010 | ||
|---|---|---|
| Physical characteristics | Form | Powder | 
| Color | White | |
| Odor | Odorless | |
| Melting point | None | |
Related laws and regulations
| TSCA | Not Listed | 
|---|---|
| EINECS | Not Listed | 
| REACH | Not Listed | 
Characteristics
1) Highly water soluble and hydrophilic
- FOM-03010 dissolves in water at 50 wt% or more. It is easily soluble in solvents such as methanol and ethanol.
- Due to the betaine structure, it exhibits very high hydrophilicity. (CLogP = -10)
 
			
Many of the hydrophilic monomers currently on the market have CLogP values of around -2 to +1, which is an index of hydrophilicity/hydrophobicity.
FOM-03010 has a CLogP value of -10 and much higher hydrophilicity than these general-purpose monomers.
			
 
			Also in the LogD value, which is a hydrophilicity index considering the dissociation of molecules under different pH environments, FOM-03010 shows high hydrophilicity with LogD = -4 (pH = 7).
MPC:2-Methacryloyloxyethyl phosphorylcholine
GLBT:Carboxymethyl betaine monomer
HEMA:2-Hydroxyethyl methacrylate
			
Solubility in various solvents and monomers
| Solvent/monomer name | Solubility at each solid content concentration (weight%) | |||||||
|---|---|---|---|---|---|---|---|---|
| 0.1 | 0.5 | 1 | 10 | 20 | 30 | 40 | 50 | |
| Water | ◯ | ◯ | ◯ | ◯ | ◯ | ◯ | ◯ | ◯ | 
| Methanol | ◯ | ◯ | ◯ | ◯ | ◯ | ◯ | × | - | 
| Ethanol | ◯ | ◯ | ◯ | ◯ | × | - | - | - | 
| Isopropyl alcohol | ◯ | ◯ | × | - | - | - | - | - | 
| Dimethylsulfoxide | ◯ | ◯ | ◯ | ◯ | ◯ | × | - | - | 
| Acetone | × | - | - | - | - | - | - | - | 
| Ethyl acetate | × | - | - | - | - | - | - | - | 
| Dimethylacetamide | × | - | - | - | - | - | - | - | 
| 2-Hydroxyethyl methacrylate (HEMA) | ◯ | ◯ | ◯ | ◯ | × | - | - | - | 
| N-(2-Hydroxyethyl) acrylamide | ◯ | ◯ | ◯ | ◯ | ◯ | × | - | - | 
| N,N-Dimethylacrylamide | ◯ | × | - | - | - | - | - | - | 
| 4-Acryloyl morpholine | ◯ | × | - | - | - | - | - | - | 
※Measured at liquid temperature of 25°C
※ 🞅: Soluble 🞨: Insoluble -: Not measured
2) Excellent in hydrolysis resistance
- Excellent in hydrolytic resistance in acidic to basic aqueous solutions.
3) Highly biocompatible
- Resistant to cell adhesion and platelet adhesion. *Based on the test by FUJIFILM
Verification of the inhibitory effect of cell adhesion
 
			Applications
Imparting biocompatibility to various products
Examples:Medical devices, materials for analytical instruments, materials for bioengineering
Hydrophilic/antifouling coating
Examples:Separating film, analytical instruments, building materials, water-absorbing materials, fibers, household products, cleaning agents
Water retaining/moisturizing materials
Examples:Additives for cosmetics and toiletry products, civil engineering materials, sanitary goods
Control of hydrophilicity/hydrophobicity of various cured components
Examples:Paint, coating, kneaded and molded products, printing materials, gel, drug formulation materials
Usage example
- A functional coat with a high hydrophilicity can be formed.
- Due to the high water solubility of the monomer and initiator, a coat solution can be prepared using water as a solvent.
 
			Example of composition of Coat A
| Name of raw material | Compounding ratio (wt%) | 
| Water soluble crosslinking agent (FOM-03006) | 30 | 
|---|---|
| Water soluble monomer (FOM-03010) | 67 | 
| Water soluble light radical initiator (FOM-03011) | 3 | 
| Methanol | 400 | 
Usage example and physical characteristics of Coat A
- Apply to PET substrate, dry (50°C/5 min), and then photocure (3 J/cm2)
※Lamp used: High pressure mercury lamp (Exposure is controlled as UV-A)
| Coats evaluated | Water contact angle (°) | 
| PET alone | 75 | 
|---|---|
| Coat A | 35 | 
| Impregnate Coat A with water and dry | 44 | 
In evaluation of wettability by water contact angle showing affinity with water, Coat A exhibits high hydrophilicity with a low contact angle, and maintains the hydrophilicity even when it is re-dried after being impregnated with water.
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